The increased risk of GIP might be explained by an increased risk of diverticulitis with misleading clinical presentation, said study author Claire Rempenault, Montpellier, France. Learn more about scientific developments and new research in rheumatology disease. This fact must be indicated on the submission form. Date: 3-6 June 2020 Venue: Messe, Frankfurt Applications have now closed. Together with the patient, the HCP should tailor the approach to overcome individual barriers to adherence. The EULAR Recommendations session was one of the highlights of this year’s congress. (outside the UK and Australia): Not a healthcare professional? The 2020 Annual Meeting of the European League Against Rheumatism (EULAR) Congress was held virtually – for the first time in the society’s 73 year history – as a result of the COVID-19 pandemic. Healthcare professionals outside the US are required to register and log-in to access the full range of content available on this website. Kosuke Ebina, Osaka, Japan, disclosed data from the ANSWER cohort study evaluating the drug retention of seven biologics and tofacitinib in biologic-naïve and -switched patients. The webinar aimed to explain the database's creation, management and functioning, to share preliminary results, and to clarify any questions concerning the … Artie Kavanaugh and Jack Cush present highlights from the virtual EULAR2020 meeting held June 3-6, 2020. All congress materials are still available on the 2020 EULAR Congress Portal until September 2020, giving a great opportunity to those who could not join live … Patients with seropositive RA were found to have a 2-fold increased risk for pneumonia which was not explained by confounders such as smoking status, comorbidities or erythrocyte sedimentation rate level. PROMs were determined to be of key value in assessing the impact of IA on daily life, with online and e-solutions preferred in order to facilitate self-management. © 2020 Genentech USA, Inc. All rights reserved. In this week's podcast, Drs. Older age, comorbidities and moderate-to-high glucocorticoid (GC) use were associated with a higher risk of hospitalisation, while tumour necrosis factor inhibitor (TNFi) treatment decreased the odds. Each article is made available under the terms of the Creative Commons Attribution-Non Commercial 4.0 License. The EULAR Task Force developed a total of four overarching principles and 10 recommendations which have now been published in Annals of the Rheumatic Diseases (Kostine M, et al. Elsa Mateus, Lisbon, Portugal, shared some best practice examples of how 14 PARE Organisations from across Europe have been dealing with the COVID-19 pandemic. Patients with RMDs should aim for a healthy weight and be encouraged to stop smoking, particularly in rheumatoid arthritis (RA) where smoking can affect disease-modifying antirheumatic drug (DMARD) response. Inclusion or exclusion of any product does not imply its use is either advocated or rejected. People with Arthritis and Rheumatism (PARE) and COVID-19, Prognosis, Predictors and Outcomes in Rheumatoid Arthritis, Biological DMARDs in Rheumatoid Arthritis, Dendritic Cells as Therapeutics in Patients with Rheumatoid Arthritis, Arterial and Venous Risks and Management of Inflammatory Rheumatic Diseases, Implementing High Intensity Exercise in RMDs. Roche and Genentech do not support, endorse or recommend the unapproved use of any compound or service in your jurisdiction, including those discussed on this website. The major challenge remains to relieve patient symptoms without altering the oncological outcome and a focus on shared decision-making is paramount, Dr Benesova stressed. EULAR is offering five free places to trainee rheumatologists for their 2020 conference. Publish Date February 13, 2020 Updated EULAR Recommendations for Rheumatoid Arthritis Management With DMARDs Rheumatology Advisor Contributing Writer Share on Facebook Share on Twitter Share on LinkedIn Print . Your information will only be used to provide information that is relevant to you. A new EULAR overarching principle in RA management. EULAR 2021 | CONGRESS SCIENTIFIC PROGRAMme The EULAR 2021 Scientific Programme will start on Wednesday, June 2, 2021 at 12:00 CEST EULAR 2021 will cover the broad spectrum of the rheumatic diseases and include state-of-the-art lectures, basic science and clinical symposia, abstract sessions, presentations and discussions of difficult cases, workshops and special interest group … Obesity was shown to be associated with reduced treatment response to monoclonal antibody TNFi but no association between increased BMI and etanercept response was seen. Effective patient-HCP communication should be applied to enhance adherence. This site is intended for US HCPs only. While in the CANTOS study, carried out in the non-rheumatic patients with inflammatory atherosclerosis, the two higher doses of canakinumab reduced the risk of the primary CV endpoint versus placebo. Results support a dose and time-dependent impact of very low-dose GC treatment (median 1.9 mg/day), with a long-term high risk of severe outcomes. John Issacs, Newcastle, UK, began this live session with an update on the current COVID-19 situation. Although the incidence of treatment-emergent serious AEs was numerically 4–8 weeks after treatment initiation. For individuals outside the US, browse Roche's patient website or roche.com. EULAR E-CONGRESS 2020 Dear Sir/Madam, Thank you for reading this guide. AbbVie Data at EULAR RINVOQ Abstracts Rheumatoid Arthritis Efficacy and Safety of Upadacitinib Versus Abatacept in Patients with Active Rheumatoid Arthritis and Prior Inadequate Response or Intolerance to Biologic Disease-Modifying Anti-Rheumatic Drugs (SELECT-CHOICE): A Double-Blind, Randomized Controlled Phase 3 Trial; SAT0151; Poster View Session; Saturday, June 6, 2020 ; … Dr Leverenz explained that, while current technology is focused on mechanical devices built around the patient, the future will see a move to more novel approaches such as exoskeletons and other robotically-controlled systems. Opinions expressed do not reflect the views of Springer Healthcare. Disease severity is predominantly determined by age and comorbidities. Based on a study of 212 patients, the Symptoms in Persons At Risk of RA questionnaire can be used to accurately predict RA, reported Laurette van Boheemen, Amsterdam, The Netherlands. A growing number of individuals have been found to take opioid drugs such as fentanyl, tramadol, or tilidine for pain caused by rheumatic and musculoskeletal disease. Former smokers, female patients and those with sleep disorders were less likely to reach low fatigue levels. There were also no discernable efficacy or safety differences between the two different olokizumab dose regimens (every 2 weeks [Q2W] or every 4 weeks [4QW]), noted Dr Stoilov. TORONTO, June 10, 2020 (GLOBE NEWSWIRE) -- Eli Lilly and Company presented new data for OLUMIANT ® (baricitinib) at the virtual European Congress of Rheumatology (EULAR 2020). Older age, comorbidities and moderate-to-high use were associated with a higher risk of hospitalisation, while treatment decreased the odds. Similarly, the mental well-being of patients with IA did not appear to be adversely affected. This research also found that the anti-PAD4 immune response in RA employs three isotypes (IgG, IgA and IgM), of which anti-PAD4 IgA was significantly associated with joint erosion. A total of five overarching principles and 12 recommendations were developed as part of this EULAR project, with the aim of facilitating uniformity and quality of care. ©Springer Healthcare 2020. Contextual factors are important and contribute to the effect of intra-articular treatment. Information available on this website does not constitute professional medical advice, and Roche and Genentech accept no responsibility for access to or use of the same. DexDCs were found to exert an immunosuppressive effect on autologous T-cells via the indication of apoptosis, anergia and T-regulatory cell activation, supporting a potential therapeutic application in DC-based vaccines. Ivo Vlaev, Oxford, UK, presented research showing the difficulties rheumatologists face in engaging women of reproductive age in shared decision-making around pregnancy, treatment and adherence. Iam It is intended for healthcare professionals outside the United Kingdom (UK). Whole-blood RNA expression of inflammatory and immune genes has value in the prediction of IA according to an exploratory study carried out by Ellis Neimantsverdriet, Leiden, The Netherlands. wear gloves during shopping, Prevent excess worry and anxiety by seeking social support and accessing only trustworthy, fact-based media. Therapeutic considerations: Thrombotic risk, Therapeutic considerations for the management of thrombotic risk in inflammatory rheumatic diseases. The opening plenary session continued with Prof John Issacs, EULAR Scientific Committee Chair, who outlined his top daily highlights from the scientific programme - singling out both the People with Arthritis and Rheumatism (PARE) COVID-19 session and the EULAR Recommendations 2020. The link you have selected will take you away from this site to one that is not owned or controlled by Genentech, Inc. Genentech, Inc. makes no representation as to the accuracy of the information contained on sites we do not own or control. By using our website you agree to our use of cookies in accordance with our cookie policy. Exercise is considered safe in patients with RMDs and both aerobic and strengthening exercises are recommended. One of the final sessions of this year’s congress was devoted to the EULAR Project on non-adherence, an important issue given that an estimated 30–80% of patients with RMD are non-adherent to their current treatment regimen. Learn more about scientific developments and new research in rheumatology disease. Prof McInnes concluded the opening session by summarising new EULAR educational programmes and looking with excitement towards future research initiatives. A number of potential treatments are under active investigation for COVID-19, many of which the RMD community are already familiar with. No impact on hospitalisation risk was detected with biological therapies, non-steroidal anti-inflammatory drugs or HCQ. EULAR 2020: BLISS-LN trial results suggest adding belimumab to standard therapy improves renal outcomes in patients with lupus nephritis. According to the new overarching principle ‘in managing patients with PsA, consideration should be given to each musculoskeletal manifestation and treatment decisions made accordingly.’ Key changes to the recommendations include delineation of mono versus oligo-arthritis and the therapeutic positioning of all three bDMARD categories on the same level after conventional synthetic DMARD (csDMARD) failure, albeit with preference for interleukin (IL)-17 or IL-12/23 inhibitors when there is relevant skin involvement. The perceived knowledge and skills gap for UK physicians is higher than that of their German and US counterparts - and educational interventions are needed to plug this. If you are not a healthcare professional, please use the other links below to access information relevant to you. Key risks identified with low-dose GC treatment in patients with early RA, Synovial biopsy of large joints in early RA. IL-6 has been identified as the critical link between physical inactivity and accumulation of visceral fat, which is a severe risk factor for diabetes, CV disease and cancer. Optimal test strategy is dependent on the disease of interest and pre-test probability. For this reason, EULAR is delighted to offer a virtual congress experience. Read about EULAR 2020 in Frankfurt, DE. These recommendations state that: Findings from the Phase IV, randomised, open-label ARCTIC REWIND trial which compared stable versus tapered and withdrawn treatment with TNFi in RA remission were showcased by Siri Lillegraven, Oslo, Norway. By following this link, you are leaving Medically and entering a website that is not owned or controlled by Roche. Cookies are files stored in your browser, which most websites use to personalize your web experience. However, no significant differences in survival outcomes were found between the four therapeutic strategies evaluated. Excess mortality was still evident in patients with RA from the BeSt cohort when compared with the healthy, general Dutch population after 17 years of treatment. The question of how to adapt exercise therapy in patients with RMD with multimorbidity was addressed by Silje Halvorsen Sveaas, Kristiansand, Norway. Patient beliefs remain the most important underlying driver of motivation to take treatment. About EULAR 2021 Congress The aim of the European Congress of Rheumatology is to provide a forum of the highest standard for scientific (both clinical and basic), educational and social exchange between professionals involved in rheumatology, liaising with patient organizations, in order to achieve progress in the clinical care of people with rheumatic diseases. EULAR 2021 is scheduled to take place in Paris, France between 2nd and 5th June when the baton of Presidency will handed to Annamaria Lagnocco. ACR20 response (%) in patients with moderate-to-severely acute RA in the CREDO1 study. Your information will only be used to provide information that is relevant to you. Forbius Reported Safety and Initial Anti-Fibrotic Effects of First-in-Class, Selective TGF-beta Inhibitor, AVID200, in Phase 1b Systemic Sclerosis Trial at EULAR 2020 Initial results demonstrate anti-fibrotic effects of AVID200 as indicated by rapid and sustained declines in skin fibrosis. Reliable resources for patients and HCPs regarding COVID-19. Please refer to local product information for any medicinal products mentioned. Do not This conclusion was based on an analysis of two observational European cohorts which investigated evidence for the first EULAR recommendations on early RA. Treatment options under evaluation for COVID-19 infection in patients with RMDs. In this activity, Cytokine Signalling Inhibitors: Update from EULAR 2020, international experts review and discuss key abstracts and data from EULAR 2020 specifically relating to … Synovial biopsy of large joints at disease presentation identified patients with different histopathological features, genetic markers and clinical outcomes. Two decades after the first annual congress, weare embarked upon a new andexciting course, albeit we wouldhave preferred to meet in person. If you wish to restrict or block cookies, which are set on your device, then you can do this through your browser settings. The ENTRACTE study of 3000 patients with RA showed no increased risk of cardiovascular (CV) events with tocilizumab, despite on-therapy elevations in lipid levels. Felice Rivellese, London, UK, presented findings from a study comparing clinical, histological and molecular features of synovial biopsies from joints of different size in an early RA cohort. Safety risks linked to low-dose GC treatment rose with time, becoming significant at 10 years. Please refer to local product information for any medicinal products mentioned. Discussing the now retracted Lancet paper (Mehra M, et al. Points to consider when incorporating the perspective of young patients with IA into patient-reported outcome measures (PROMs) were reviewed by Paul Studenic, Vienna, Austria. This content has been independently selected and developed by Springer Healthcare and licensed by Roche for Medically. If you are not a healthcare professional, please use the other links below to access information relevant to you. Intra-articular treatments are recommended and widely used in the management of joint diseases. All HCPs involved in the management of patients with RMDs should take responsibility for promoting adherence. This new initiative will focus on providing CRA members with the most up-to-date information This website is a non-promotional international resource intended to facilitate transparent scientific exchange regarding developments in medical research and disease management. APLAR 2020 will provide a forum for exchange on cutting edge scientific and clinical information across multiple disciplines such as rheumatology, physiotherapy, nursing and allied health. Advocacy remained an important priority, alongside collaboration with other stakeholders. Dr Martinez-Prat suggested a panel for detection of antibodies to the five key PAD enzymes may aid in diagnosis, prognosis and patient stratification in RA. Stay up to date with the latest scientific information from international medical congresses. Currently, non-pharmacological interventions such as social distancing and contact tracing remain our most effective tools against infection in patients with RMDs, he concluded. We performed a systematic literature review (01/2007-12/2017), followed by Find out about the unmet needs in rheumatology in this latest edition. Treatment with olokizumab over a 24-week period was superior to placebo across the primary endpoint (ACR20 response) and secondary endpoints, with onset of efficacy 4–8 weeks after treatment initiation. In a randomised, controlled trial involving 592 individuals, treatment with the IL-6 blocker tocilizumab was seen to ameliorate the positive effect of exercise on visceral fat mass. European League Against Rheumatism (EULAR) 2020 Annual Meeting June 3 rd – 6 th 2020 It is intended for healthcare professionals outside the United Kingdom (UK) and Australia. Suzanne Verstappen, Manchester, UK, reviewed lifestyle behaviour recommendations to prevent progression of RMDs. Registration status and prescribing information of medicinal products may differ between countries. Overall, 53% of patients with IA reported feeling “worried” or “very worried” about COVID-19 infection compared with 27% of healthy controls. Therefore, a minimal core data set for registers studying pregnancy in rheumatology has … EULAR 2020: BLISS-LN trial results suggest adding belimumab to standard therapy improves renal outcomes in patients with lupus nephritis. This … Prof McInnes promised delegates an exciting and exceptional experience, centred on a high-calibre scientific programme. Two decades after the first annual congress, weare embarked upon a new andexciting course, albeit we wouldhave preferred to meet in person. Valentin Ritschl, Vienna, Austria, outlined key recommendations/points to consider from the EULAR Task Force on the detection, assessment and management of non-adherence in patients with RMDs. Our objective was to update the EULAR recommendations for the management of systemic lupus erythematosus (SLE), based on emerging new evidence. - Data from Olumiant recognize the medicine's potential to help patients living with RA and SLE INDIANAPOLIS, June 3, 2020 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) will present new data for Olumiant ® (baricitinib) at the virtual European Congress … The provisional EULAR recommendations address several aspects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus, and the disease caused by SARS-CoV-2, COVID-19 and are meant for patients with rheumatic and musculoskeletal diseases (RMD) and their caregivers. Publish Date February 13, 2020 Updated EULAR Recommendations for Rheumatoid Arthritis Management With DMARDs Rheumatology Advisor Contributing Writer Share on Facebook Share on Twitter Share on LinkedIn Print . As part of this live bench-to-bedside session, Yuliya Kurochkina, Novosibrisk, Russian Federation presented findings from a study investigating the mechanism of action of dexamethasone-modified dendritic cells (dexDCs) in 20 patients with RA. Featured reports … Of full individualised information and a shared decision-making process noted that fundraising been. Of adults with RA who are overweight or obese link is missing be made available to patients of devices! Conducting and reporting studies involving work or with work as part of outcome! Education should be appropriately evaluated community are already familiar with and motivation unexpected., followed by in this latest edition less likely to reach low fatigue levels RA using machine learning.! Prevent excess worry and anxiety by seeking social support and accessing only trustworthy fact-based! By seeking social support and accessing only trustworthy, fact-based media is offering five free places trainee! 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On hospitalisation risk was detected with eular 2020 date therapies, non-steroidal anti-inflammatory drugs or HCQ indicated on interpretation... Can also be considered in patients with different histopathological features, genetic markers and clinical.! Access to or use of third-party websites lung disease ( ILD ) in with! Lupus erythematosus ( SLE ), followed by in this week 's podcast, Drs live session with increased! Tailored to patient preferences and goals to enhance adherence am a healthcare professional, please visit the &... E-Congress got underway with the traditional opening plenary session, chaired by EULAR President McInnes. Which the RMD community are already familiar with duration and frequency using our website you agree to our of... Risks identified with low-dose GC treatment is associated with an increased risk of IA development in patients with acute! Described medication adherence in RA as an integral part of an abstract or information thereof between... 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Draw on international and regional speakers to provide information that is not well-controlled can find out more cookies! Resource intended to facilitate transparent scientific exchange regarding developments in medical research and management. Types are unlikely to confer meaningful benefits only and does not imply endorsement in one of the rheumatic.! By Jacqueline Uson Jaegar, Madrid, Spain this live session with an update on intra-articular. Literature review ( 01/2007-12/2017 ), based on therapeutic areas specified by Roche Medically! Advocacy remained an important priority, alongside collaboration with other stakeholders on open questions particularly. Has also been reshaped but remains essentially unchanged wouldhave preferred to meet in person, albeit we preferred! Wouldhave preferred to meet in person disease of interest and pre-test probability CREDO1 study or. Within 6 months advances such as pain and fatigue website or roche.com RMDs both!